Strategic thinking and packing along with a good sense of humor can be your greatest strengths when it comes to offsetting the many physiological stressors and degenerative impacts of flying at 12,500 – 50,000 feet on a regular basis. Even though you may think your patience is the system that’s most stressed on a regular basis, your Circulatory and Respiratory systems are really the ones most affected, even in pressurized cabins.